When meals get smaller, protein can drop quickly
As the discontinuation rates were also high with the twice daily danuglipron at the phase 2 obesity trial (as discussed above), twice daily danuglirpon formulation will not advance into phase 3 studies, but an improved once-daily formulation with an aim to improve tolerability profile is currently under assessment [27]
When asked about the results of the study, Amber Alhadeff , a neuroscientist from the Monell Chemical Senses Center, stated that she believes they open a door in terms of GLP-1 possibilities
Funding The author(s) declared that financial support was not received for this work and/or its publication
GLP-1, in addition to its known effects on stimulating beta-cell proliferation and inhibiting apoptosis, is involved in the modulation of trans-differentiation and de-differentiation processes [7]
Does intervention with GLP-1 receptor agonist semaglutide modulate perception of sweet taste in women with obesity: study protocol of a randomized, single-blinded, placebo-controlled clinical trial