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Closing remarks Incretin-based AOM are currently in the spotlight as the most efficacious weight loss treatment to date 113 , exhibiting also beneficial effects on the complications of excess adiposity such as T2D, cardiovascular disease, heart failure, MASLD, OSA and possibly others

In line with this suggestion, ketogenic diets lower alcohol intake (135) and abstinence symptoms (135, 136)

The recommendations of the PCAC are non-binding but noteworthy

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Notably, AOD9604 also appears to interact with HSL and ACC, but does not support carbohydrate metabolism or insulin sensitivity