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Alpha-melanocyte stimulating hormone in the skin It is -MSHs role In stimulating melanin production (melanogenesis) in the skin which is arguably best understood

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Other drugs, such as monoamine oxidase B (MAO-B) inhibitors (e.g., rasagiline, safinamide, selegiline) or catechol-O-methyltransferase (COMT) inhibitors (e.g., entacapone, tolcapone), may also be used to improve dopamine levels, although sometimes symptoms may persist or worsen even with optimized dopaminergic therapy (Pardo-Moreno et al., 2023

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