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Blood levels of 4-hydroxy-2-nonenal (4-HNE)-modified DJ-1 were significantly higher in PD patients than those in controls, which were even higher in patients with advanced PD than those in patients with early PD

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The B-complex vitamins, particularly B1 (thiamine), B6 (pyridoxine), and B12 (cobalamin), are involved in alcohol metabolism and can become depleted during heavy drinking