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It has not been possible to determine which symptoms are due to carnitine deficiency and which are due to an underlying organic acidemia, as symptoms of both abnormalities may be expected to improve with levocarnitine

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256 In addition, ethanol could activate kinase CK2 to phosphorylate MAT1 at Ser114, promote its interaction with PIN1 isomerase, inhibit MAT1 localization in mitochondria, and promote ethanol-induced mitochondrial dysfunction and fat accumulation

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