It is also worth examining closely, because the science of getting a GLP-1 molecule through your skin is far less forgiving than the marketing suggests
-22.5% weight on 15mg, 72 wks, N=2539
Lately theres been a wave of products like Inno Shred GLP-1 that market themselves as weight-loss game changers, but they dont have semaglutide, tirzepatide, or any other GLP-1 meds inside
Administration of CCK, in humans and animals, inhibits food intake by reducing meal size and its duration.17,18 Recent work suggests that CCK-A receptors expressed by vagal afferent neurons are an important target for CCK in producing sensations of satiety, as well as inhibiting gastric emptying and stimulating pancreatic digestive enzyme secretion.19 In animals it is thought that the reduction in food intake may be mediated by a paracrine/neurocrine effect since high concentrations of CCK occur only locally to the site of release.20 Thus, locally released CCK may increase vagal tone, without a significant increase in plasma CCK level
This remains an area of active research rather than established clinical practice, and until adequately powered, randomised controlled trials assess the safety and efficacy of this specific combination, clinicians and patients should approach any claims about its benefits with appropriate scepticism
I would definitely recommend to my family and friends
