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One of the side effects that have been reported is quite similar to other injectable incretin-based therapies

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The medication's effects on gastric emptying provide a plausible biological mechanism for why reflux symptoms might occur in some individuals, though a direct causal relationship has not been firmly established in clinical studies

observed a correlation between high CHAC2 levels and mutant TP53, potentially due to hypomethylation of the CHAC2 promoter

Expression levels of the (A) AMPK and (B) SIRT6 genes and their associated proteins were analyzed using quantitative real-time polymerase chain reaction (qRT-PCR) and Western blotting, and -actin was used as the loading control