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Among these, only 23.53% developed disease recurrence, as opposed to 60% of patients who underwent STR

Most patients report reduced appetite and smaller portion sizes within the first few weeks, which gradually translates into measurable weight reduction

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Thus, while more in vitro and in vivo evidence of a role for NRF2 in preserving the NSC pool in neurodegenerative disease is needed, these studies clearly indicate that loss of NRF2 is detrimental during age-related pathogenesis, and that NRF2 activators could be of therapeutic benefit for this subset of diseases, partly by promoting NSC survival

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