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doi: 10.3389/fimmu.2021.6 272 TaylorE

Given the progressive nature of the disorder, disease pathogenesis is mainly triggered by continual processes such as geometric accumulation of oxidative radicals brought about by cellular inclusions and mitochondrial dysfunction 8,9,10

The Pyo et al

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In the context of mast cell-driven inflammation, these markers offer insight into how far the inflammatory process has progressed into neural tissue