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Predicted peptide structures from PepStrMod and Iterative Threading ASSEmbly Refinement aid design candidates, but predicted tertiary structures, 153 were successfully modeled, require in vivo testing

Knockdown of one factor in the pathway may improve but not fully disrupt the muco-inflammatory cycle due to the multifactorial and overlapping regulators of mucin secretion

Together, these compounds provide researchers with a dual-peptide model suitable for studying complex signalling networks and peptide interaction dynamics within controlled research environments

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