Medications make more sense for people with significant weight to lose for health reasons, those with type 2 diabetes or prediabetes where GLP-1 receptor agonists address both conditions simultaneously, individuals who have tried lifestyle changes and supplements without adequate results, and anyone whose healthcare provider recommends pharmaceutical intervention based on risk assessment
This can impact how quickly weight loss occurs with Tirzepatide, as older adults may need more time to witness significant changes
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4 Acute coronary syndromes and stable angina (NICE NG185) 7 7 Offer people who have suffered a myocardial infarction an ACE-I (or ARB) as soon as they are haemodynamically stable for secondary prevention of cardiovascular disease (alongside dual antiplatelet therapy, beta-blockers and statins), and continue indefinitely
En los ensayos clnicos esto se traduce en una prdida de peso media superior a la de los GLP-1 mono-agonistas en adultos con obesidad