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Research shows that people who used semaglutide had lower vitamin B12 levels (they also had bariatric surgery before using semaglutide), and another study concluded that people with obesity had lower B12 levels

Why Vitamin B12 Matters Among the most important nutrients, vitamin B12 is crucial to health

Minimizing Methylmalonic Acid Levels Appendix B

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Researchers also observed shifts in glucose uptake and sirtuin activity (the SIRT1 longevity protein family) when NNMT was blocked

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