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First therapeutic testing of GLP-1 in humans By the late 1980s two versions of GLP-1 were separately beginning to be tested for their therapeutic potential

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108 Dulaglutide Dulaglutide was approved by the FDA in 2014 for the treatment of T2DM

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Liraglutide is an injectable drug taken once a day, while semaglutide is an injectable drug taken once a week or an oral drug taken daily

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Reduce dietary fat intake, as high-fat foods are particularly difficult to digest when gastric emptying is delayed

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doi: 10.1586/17512433.2016.1121808 107 JendleJGrunbergerGBlevinsTGiorginoFHietpasRTBotrosFT

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Figure 2

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