Neuroprotection mediated through estrogen receptor-alpha in astrocytes
It may cause some common mild side effects such as flushing or an overall feeling of warmth, upset stomach including nausea and vomiting, breast tenderness, headache, dizziness, abnormal vaginal bleeding, and blurry vision
Psychological issues include stress, anxiety, relationship problems, and depression
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Furthermore, certain clinical drugs with metal-chelating properties have shown promise in preventing ferroptosis by interfering with iron-related processes
Distinct advantages of TDDS over other drug delivery systems include self-administration, sustained drug release, and reduced dosing frequency