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Excess secondary antibody was washed off by 3 consecutive 10-min rinses with PBST
However, under oxidative stress, oxidative modification of cysteine residues in Keap1 causes conformational changes that weaken its binding to Nrf2, allowing Nrf2 to dissociate from Keap-1 and rapidly translocate to the nucleus
Highly Luminescent Thiolated Gold Nanoclusters Impregnated in Nanogel
Ultimately, these mechanistic benefits play out in clinical trials, where ALCAR supplementation has been shown to improve cognitive function and slow neurodegeneration [22]
Images obtained were analyzed using Fiji ImageJ