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doi: 10.1007/s00425-023-04232-x 37 WuCJShanWLiuXCZhuLSWeiWYangYYet al

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For instance, research shows MOTS-c drives glucose into the pentose phosphate pathway (for anabolic needs and antioxidant defense) rather than burning it immediately via glycolysis, while simultaneously increasing fatty-acid oxidation by upregulating carnitine shuttle activity in mitochondria

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Rather than blocking a single cytokine outright, many peptides modulate upstream regulatory pathways