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The research also revealed that there is "a drive to prescribe, rather than making sure the patient is going to be safe in taking these medications and that the medication is going to be appropriate for them," Ramachandran said.

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In animal models, retatrutide reduced food intake , body weight , and glycemic markers more than GLP-1 monotherapy and dual GLP-1/GIP agonists

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Studies demonstrated significant reductions in visceral adipose tissue (VAT) within 6 to 12 weeks of consistent daily administration, with effects maintained for the duration of treatment