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The doses are super off compared to anything that was in research studies, like they were giving people 8,000 times the dose of what is in the patch, she says

Patients with a history of pancreatitis face substantially higher recurrence risk and should discuss alternative treatments with their healthcare provider, as FDA labeling advises considering other therapies in this population

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This objectively quantifies changes in visceral fat, subcutaneous fat, and lean mass, allowing researchers to evaluate whether the combination is producing the hypothesized benefits (preferential visceral fat loss with muscle preservation)