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Recent reports indicate the absence of functional GLP-1R in liver parenchymal cells, suggesting that the observed hepatic effects of GLP-1RA are likely indirect and may be mediated through extrahepatic of gut-liver signaling pathways [35,36,37]

Remarkably, users who started GLP-1 treatments within this timeframe account for nearly one-quarter of the Total Store unit decline, underscoring the broader market impact of these medications, Nielsen said

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It is not specific to GLP-1 drugs