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The FDA has recognized laxative products to be safe and effective in the general population when used according to label instructions [6]

The most classical way of interaction between the gut microbiota and the host is via the metabolites the bacteria produce

The crosstalk between intestinal bacterial microbiota and immune cells in colorectal cancer progression

Chronic daily use risks toxicity (e.g., serotonin syndrome, organ strain) and lacks mainstream medical approval for daily wellness claims

Eli Lilly, Novo Nordisk's main competitor for diabetes and weight loss medication, still holds its patent in Canada and there's no imminent patent expiry for its drugs: Mounjaro and Zepbound

According to Contraves website, the lowest people might pay for the drug with insurance coverage is around a $20 copay per month