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This increase in ROS triggers mitochondrial dysfunction, further exacerbating oxidative stress and promoting cell death through both necroptosis and ferroptosis pathways (Figure 5) (Table 1, we present a comparative analysis of other proteins involved in cancer treatment, particularly those influencing ER stress or ferroptosis

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Administration of Bifidobacterium breve improves the brain function of A1-42-treated mice via the modulation of the gut microbiome