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People need to know from the start that these are prescribed as long-term medications for their effect on body weight, glucose levels, and potentially cardiovascular protection, Pratley says, adding that people dont stop antihypertensives or statins because they achieve or reach normal blood pressure or LDL cholesterol levels, respectively

reported that GLP-1RAs can promote the overactivation of GLP-1R in pancreatic cells, which not only increases susceptibility to pancreatic inflammation but also increases the risk of pancreatic cancer