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The clinical relevance of these potential interactions in humans remains uncertain, and more research is needed to determine whether berberine meaningfully affects metformin's pharmacokinetics

Its important to note that initial weight loss might include water weight, and achieving long-term fat loss requires ongoing commitment to healthy habits

This includes proper management of high blood pressure, diabetes and cholesterol all conditions that compromise the small blood vessels feeding the optic nerve

[1] Cani, P

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This may appeal to those who prefer botanical approaches