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The recommended dietary allowance for vitamin B12 in someone with normal absorption is only about 2.4 mcg per day, according to the Food and Nutrition Board

These claims are then assigned one unit of the service with status indicator J1 and later used to develop the geometric mean costs for the C-APC relative payment weights

Starting with 10mg vials for the first 8 weeks and transitioning to 20mg or 30mg vials for the maintenance phase is the most cost-effective and practical approach for most research protocols

That is not arbitrary

For CY 2026, except where otherwise indicated, we proposed to use the costs derived from CY 2024 claims data to set the proposed CY 2026 payment rates

How often you need a b12 injection will depend on your individual situation