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According to a study by Obeid et al., a widely accepted expert consensus on diagnosing and treating vitamin B12 deficiency, recognized that untreated deficiency can lead to irreversible symptoms
The key findings from this clinical program include significant reductions in body weight and fat mass in treatment groups compared to placebo, preferential loss of abdominal and visceral adipose tissue, no changes in serum IGF-1 levels at any dose tested, no negative effects on glucose metabolism or insulin sensitivity, no significant adverse events related to metabolic or endocrine disruption, and safety profile indistinguishable from placebo for most parameters
What is the critical difference between vitamin B12 liquid and pills
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So, if you take only folate, you might not know if you are low in vitamin B12, and if you take only vitamin B12, you might not know you are low in folate