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That said, there are a few exceptions

These three synthetic strategiesprodrug design, deuterium labeling, and PEGsulfonate conjugationillustrate modern medicinal chemistrys role in enhancing safety of legacy antipsychotics

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In particular, glucagon has firmly been demonstrated to enhance hepatic lipid metabolism, Hepatic GCGR agonism leads to upregulation of lipid catabolism pathways in the hepatocyte where a number of key regulatory transporters and enzymes facilitate beta oxidation of fatty acids (61)

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