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Tirzepatide (26.6%) but long-term safety and effectiveness are still being studied for retatrutide

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In this context, the data currently available on tirzepatide, showing its efficacy in glycemic control to the extent that a considerable percentage of patients achieve glucose levels indicative of diabetes remission [3, 59], as well as its high effectiveness in weight management, are promising regarding its future use in clinical practice

Although the renoprotective effects of SGLT-2 inhibitors are maintained at these eGFRs, the glucose-lowering effects of SGLT-2 inhibitors are significantly impaired at low eGFRs

GLP-1 RAs have shown promising effects in the treatment of HS, but limitations exist in the current literature