The synthetic derivative of curcumin biphenyl-difluoroketone (EF24) has been reported to trigger cell apoptosis, restrain cell growth, and diminish metastatic capabilities (194, 195)
Sources conflict on whether fosgonimeton is a prodrug of Dihexa or a structurally distinct molecule, so it should not be read as evidence for or against Dihexa specifically only as the nearest human data point in the program, and a negative one
(2017), authored by researchers at Erasmus University Medical Center, demonstrated selective elimination of senescent cells in aged mouse models and helped drive broader interest in senolytics research
Semaglutide, a Glucagon Like Peptide-1 Receptor Agonist with Cardiovascular Benefits for Management of Type 2 Diabetes
You can report any suspected side effects to the MHRA Yellow Card scheme at yellowcard.mhra.gov.uk
The pharma has previously announced that REDEFINE 1 is expected to read out by the end of the year, while data from REDEFINE 2 are expected in the first half of 2025
