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Hidden killers: human fungal infections

The reduction of roGFP2(S 2 ) is therefore a good example for an enzyme using an alternative reaction pathway to overcome a kinetic challenge, and we hypothesize that other non-glutathione disulfide substrates with reactive proximal cysteinyl residues and rather negative redox potentials also require a ternary complex for their reduction

PMID: 199 Lo ConteMCosorichIFerrareseRCencicchioMANobiliAPalmieriVet al

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Therapies for rare diseases: therapeutic modalities, progress and challenges ahead

Once this process is completed, the body can regenerate a new protective glutathione molecule, and repeat the process