11 Additionally, a significant amount of the weight loss induced by GLP-1 drugs is derived from lean muscle tissue, which is crucial for health and longevity
Incretin-based multi-agonists, such as tirzepatide and retatrutide, target two or more receptors among GLP-1, GIP, and GCGR to enhance insulin secretion, improve fat metabolism, and increase energy expenditureultimately achieving greater weight loss and metabolic improvement
So, while there arent any explicitly prescribed GLP-1 foods to avoid, there are some science-backed recommendations for what to eat on tirzepatide (Mounjaro) and semaglutide (Ozempic)
Serotonin is a chemical in your body that affects mood, digestion, and sleep
Diabetes Care (2010) 33:221724
The principle remains intellectually compelling and mechanistically supported, but clinical demonstration of superiority based on signaling bias alone has yet to be robustly established for most peptide targets