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Three participants were lost to follow-up

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In RA, persistent synovitis and systemic inflammation underlie disease pathology, and therapies targeting pro-inflammatory cytokinessuch as DMARDsameliorate joint destruction and improve outcomes (84)

was supported by funding from the NIH NIDDK (R01 DK123075, DK125353 and DK046492), the Helmsley Charitable Trust Foundation, investigator-initiated grants from Eli Lilly, Novo Nordisk and Proteostasis, and is a Borden Scholar

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