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Mitochondrial GSH (which makes up 1015% of total cellular GSH) is the primary defense line protecting mitochondrial DNA and the electron transport chain from radical-induced degradation

Using RT, we were able to monitor the dynamic changes of GSH in living cells, which subsequently led to the observation of enhanced antioxidant capability of activated neurons and time-dependent changes of GSH during the ferroptosis process

As a final measure of peptide accuracy, our analytical lab uses mass spectrometry to verify the theoretical molecular weight of each peptide

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Finally, another clinical trial is testing the role of N-acetylcysteine as an adjuvant to opioid treatment in patients with chronic neuropathic pain (41)