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This contrasts sharply with orthobiologic therapies like PRP and mesenchymal stem cell therapies, both of which have been evaluated in multiple randomized controlled trials and large observational studies

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Microarray hybridization, scanning and quantification 200 ng of DNA extracted from fecal samples was Cy5-labelled with Bioprime DNA Labeling System (Life Technologies) and purified using the QIAquick PCR purification kit as per the manufacturers instructions