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Papers were reviewed in their entirety if their abstract mentioned that the article presented any potential relevance to the inclusion criteria

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SLC7A11, a key ferroptosis regulator, is a transmembrane protein that is part of the system Xc, responsible for cystine import into cells for cysteine synthesis and GSH production (79,80)

The advisory committee's recommendation is not binding, but historically the FDA adopts PCAC vote outcomes in its final 503A bulk substance determinations

While research is ongoing, 5-Amino-1MQs unique mechanism of action presents a promising avenue for the treatment of obesity, metabolic syndrome, and other age-related conditions

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