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These gastrointestinal side effects typically peak during weeks 6-8 and resolve significantly by week 12

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However, it is worth remembering that in the case of autoimmune, rheumatic, or inflammatory diseases, the values of lipid parameters may increase as a result of anti-inflammatory treatment of these diseases [369]

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Green et al 26 Severe clinical abnormalities should be treated intensively with B 12 , cyanoB 12 or hydroxyB 12 : HydroxyB 12 is commonly used in Europe, often at intervals of 23 months, as it seems to have better retention than cyanoB 12

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For instance, doctors might order a rheumatoid factor (RF) test specifically for rheumatoid arthritis or an antinuclear antibodies (ANA) test to screen for lupus

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