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Metabolic determinants of cancer cell sensitivity to canonical ferroptosis inducers

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We selected At SMAX1 as the substrate based on prior evidence of its interaction with Sh HTL7 and both Striga and Arabidopsis MAX2 54,55 , and because reliable Striga SMAX1 orthologues were not yet available at the time (our work began prior to the release of the annotated Striga proteome 56 )

PMID 22074294