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Key Mechanistic Differences# The mechanistic distinction is significant: Dihexa promotes structural synaptic plasticity through growth factor signaling (building new connections), while PE-22-28 modulates functional neuronal properties through ion channel blockade (changing how existing neurons fire)

Materials and Methods Primary Human Samples and Cell Line Culture Human ex vivo expanded NK cells were previously isolated from de-identified healthy donor peripheral blood mononuclear cells (PBMCs), expanded with feeder cells, and cryopreserved as stocks in liquid N 2 (20)

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Using lower level solutions (achieved by mixing with larger volumes of sterile water) may also reduce local irritation

What barrier for the BBB

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