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145,146 Inhibition of core pyroptotic mediators (NLRP3, caspase-1, GSDMD 147 ) improves hepatic histopathology in MASLD models, highlighting their therapeutic relevance

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The peptide enhances expression of key transcription factors including Lhx2 and Sox9 essential for hair follicle stem cell maintenance and activation while modulating Wnt/-catenin signalinga critical pathway for hair follicle morphogenesis and cyclingwith treated follicles showing enhanced -catenin nuclear localization and increased Wnt target gene expression

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