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doi: 10.3892/or.2015.4476 218 HeWYuSWangLHeMCaoXLiYet al

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Common side effects of GLP-1 medications include: - Nausea - Diarrhea - Vomiting - Constipation Side effects are typically mild and temporary

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Kidney Issues: Kidney damage or acute kidney injury has been reported in rare cases

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The TRIUMPH-4 Phase 3 trial tested 9mg and 12mg as the two active dose arms

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The Phase 2 trial showed 22.8% average body weight reduction at 48 weeks in the 8mg group

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Yes semaglutide and related drugs shift microbial composition, but these changes do not automatically restore microbial resilience or diversity

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