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Your digestive tract contains millions of GLP-1 receptors, and flooding them with medication before adaptation occurs triggers a cascade of adverse responses including severe nausea, vomiting, and constipation that often force dose reductions anyway

The importance of transcriptome analysis for PASC assessment is underlined by the fact that a transcriptome-wide investigation showed that processes leading to PASC already start during hospitalization for acute COVID-19 and divergent etiologies for different sets of symptoms were identified, depending on the antibody response to SARS-CoV-2 spike protein

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Bruinstroop E, van der Spek AH, Boelen A