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Larger, placebo-controlled trials are necessary to better understand how B12 works in autism and which children benefit the most

Side Effects: See Figure 2

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doi: 10.20892/j.issn.2095-3941.2025.0048 4 CaiMWangLYangWNiuJ

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In resting state, the ligand binding is uncoupled from the transmembrane domain as strain on the linkers connecting LBD to TM domains are relaxed by the extended conformation of antagonist bound LBD (even while they are in dimeric configuration)