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Mass cytometry Heavy-metal conjugation of antibodies Antibodies were conjugated to heavy-metal ions with commercially available Maxpar (Fluidigm) or MIBItag (Ionpath) reagents according to manufacturers instructions, and as previously described 30 (see Supplementary Data 2)

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Glucagon-like peptide-1 improves beta-cell antioxidant capacity via extracellular regulated kinases pathway and Nrf2 translocation