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In addition to these sources, inflammatory processes in the body are significant contributors to free radical production [8]

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Beyond energy production, NAD+ also supports several important biological processes including: Activating longevity pathways called sirtuins Supporting DNA repair mechanisms Improving mitochondrial function Helping regulate metabolic health Unfortunately, NAD+ levels naturally decline as we age

Down regulation of DJ-1 enhances cell death by oxidative stress, ER stress, and proteasome inhibition