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Petek, J

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With a molecular weight of just 403.93 Da well below the 500 Da cutoff typically associated with significant skin penetration GHK-Cu is small enough to penetrate the stratum corneum (outer skin layer) in concentrations sufficient to activate regenerative processes

Overall, RIPC is a potential mitochondria-targeted strategy for protecting the heart and kidneys from ischemia-reperfusion injury, and may be more valuable for patients with prolonged ischemia

Mongioi et al

Anti-aging context declining GH with age drives much of the longevity-oriented interest, but using these peptides for anti-aging purposes remains investigational and is not an FDA-approved indication