In one long-term study, called the SURMOUNT-1 trial, people taking tirzepatide lost up to 25% of their starting weight over a period of 72 weeks
However, RCTs utilize varying restrictive inclusion (e.g., age, disease severity) and exclusion (e.g., comorbidities, concomitant medications) criteria, leading to variabilities between patients in RCTs and those in the real world
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These hormones help control hunger, slow stomach emptying, and improve blood sugar balance, making it easier to eat less without constant cravings or feelings of deprivation
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Biosci Med