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Similarly, the comparison between tesofensine and semaglutide is relevant because tesofensine is a monoamine reuptake inhibitor that operates through stimulant-adjacent mechanisms that semaglutide does not share

It is now possible to determine the concentration of glutathione (GSH) in living human brains using magnetic resonance spectroscopy (MRS), with multiple MRS studies showing depleted brain glutathione (GSH) levels in all the major neurodegenerative diseases [6-9]

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These findings align with previous research demonstrating the therapeutic potential of natural products like Cinnamaldehyde, Sarsasapogenin-AA13, Ginkgo biloba extracts, and active components of Andrographis paniculata in targeting these pathways for AD treatment [49, 89,90,91,92]

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