Study selection and data extraction: Two reviewers screened independently
Due to the loss of the brain privilege for vitamin B2 supply, this inherited condition may be particularly relevant for CNS diseases such as migraine, brain ischemia, traumatic brain injury, neurodegenerative disorders (especially Parkinson and Alzheimers diseases), epilepsy, multiple sclerosis, and for Guillain-Barr syndrome, myasthenia, and mitochondrial myopathies
The potential involvement of a dopaminergic mechanism in this process was inferred from the blocking action of pimozide, a dopamine antagonist, on the DSIP-induced GH increase
Although this could potentially have adverse cardiac effects, GLP-1 receptor agonists have been shown to protect cardiac myocytes against ischaemia in animal and human studies
Ponzone A, Spada M, Ferraris S, Dianzani I, de Sanctis L
Systemische Anreicherung: L-Carnitin ist natrlicherweise in Herz, Muskulatur, Nervensystem und Gehirn konzentriert