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In clinical trials, people taking Contrave lost an average of approximately 8.1% of their total body weight over 56 weeks at the maximum dose

"Everyone was like, 'Oh, you already are looking like you're losing weight in just the first few days.'" Schorr said she lost 50 pounds over the course of 11 months

Diarrhea is a common side effect of Ozempic and may cause some people to stop using the drug

Weight loss accelerates (fastest velocity occurs weeks 12-24 in trials)

The diabetes drug liraglutide reverses cognitive impairment in mice and attenuates insulin receptor and synaptic pathology in a non-human primate model of Alzheimers disease

For the right patient, medications such as semaglutide and tirzepatide may be useful tools when they are prescribed, monitored, and adjusted as part of a physician-guided plan