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2.2 The effect of severe ROS buildup in IE A by-product of living organisms ordinary oxygen metabolism is ROS

Alcohol is a particular concern, as it's thought to substantially lower the body's levels of this antioxidant

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illustrated how the selective permeability of the blood-brain-barrier (BBB) and bloodCSF barrier, combined with the spatial distribution of glutathione-metabolizing enzymes, underlies region-specific vulnerability to oxidative injury in the CNS (9)

Maung, S

Jalewa J, Sharma MK, Gengler S, Hlscher C