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The authors reported a 55.8% reduction in facial wrinkle volume and a 32.8% reduction in wrinkle depth compared with control serum, alongside in vitro evidence that GHK-Cu increased both collagen and elastin production in human dermal fibroblasts at concentrations as low as 0.01 nM [4]

This includes better regulation of blood sugar levels and a reduced risk of metabolic disorders such as type 2 diabetes

A systematic review published in HSS Journal in 2025 identified only one clinical study that retrospectively assessed intra-articular injection of BPC-157 for knee pain

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What really matters is no new safety signals were identified with CagriSema beyond the known GLP-1 and amylin class effects